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Sarcoidosis with Involvement at the Large Intestine,Report of a Case
Naoyuki Yamada
※1
Sohtaroh Fukuchi
※1
※1 Department of Gastroenterology,Toranomon Hospital
The patient,29 year-old man,noted its onset through symptomes in the eyes caused by uveitis in January 1980. X-ray picture of the chest showed swelling of the bilateral hilar lymph nodes and granular shadow at the left middle lung field which led us to diagnose it as sarcoidosis. Lesions of the chest and the eyes were healed by steroid herapy. However,starting February 1984 when both lesions were in remission,anal fresh bleeding occurred at defecation. Thus,colonoscopy and barium enema were conducted and disclosed irregularly-shaped ulcerative lesions with nodular elevation in the lower rectum,and superficial mucosal lesions between normal mucosa in the descending colon. Histology of biopsy specimen taken from the rectal lesion showed epithelial cell granuloma which made us diagnose it as systemic sarcoidosis at the large intestine. After steroid therapy,melena disappeared and endoscopy showed marked improvement of the lesions.
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